B cell infiltration of the thymic medulla in new zealand black, new zealand white, and (new zealand black × new zealand white)f1 mice
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چکیده
منابع مشابه
Sialoadhesin deficiency does not influence the severity of lupus nephritis in New Zealand Black x New Zealand White F1 mice
INTRODUCTION Systemic lupus erythematosus (SLE) is a chronic inflammatory condition with multisystem involvement. One of the key features of the disease is the upregulation of type I interferons, resulting in the so-called "interferon signature". Recent flow cytometric and transcriptomic studies identified Sialoadhesin (Sn, CD169) as an important interferon-induced blood monocyte biomarker in d...
متن کاملTerminal deoxynucleotidyl transferase deficiency reduces the incidence of autoimmune nephritis in (New Zealand Black x New Zealand White)F1 mice.
Terminal deoxynucleotidyl transferase (TdT) enzyme activity in lymphocytes generates diversity in the Ag receptor repertoires by adding template-independent N nucleotides and disrupting homology-directed rearrangements. The importance of this diversity in vivo and the significance of the suppression of TdT during fetal life remain uncertain. Previous studies have shown that in TdT knockout mice...
متن کاملPrevention of autoantibody formation and prolonged survival in New Zealand black/New Zealand white F1 mice fed dehydroisoandrosterone.
Dehydroisoandrosterone, administered orally to New Zealand Black/New Zealand White F1 hybrid mice, prevented the formation of antibodies to double-stranded DNA and prolonged survival in this murine model of lupus erythematosus.
متن کاملCoote New Zealand Futures Trust New Zealand
On Media A workshop report from US Institute for Peace examined Arab media, August, 05 (http://usip.org/virtual diplomacy/publications/reports/18.html), with special focus on attitudes to US and to the West. The relevant Arab governments play a double role since mostly, they control the media, where they appease the ideological positions of their own threatening insurgencies while focusing publ...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1990
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780330513